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Polytetrafluoroethylene (PTFE) is a synthetic fluoropolymer of tetrafluoroethylene that has numerous applications. The commonly known brand name of PTFE-based compositions is Teflon by Chemours, a spin-off from DuPont, which originally discovered the compound in 1938.Polytetrafluoroethylene is a fluorocarbon solid (at room temperature), as it is a high-molecular-weight polymer consisting wholly of carbon and fluorine. PTFE is hydrophobic: neither water nor water-containing substances wet PTFE, as fluorocarbons exhibit mitigated London dispersion forces due to the high electronegativity of fluorine. PTFE has one of the lowest coefficients of friction of any solid.
Polytetrafluoroethylene is used as a non-stick coating for pans and other cookware. It is non-reactive, partly because of the strength of carbon–fluorine bonds, and so it is often used in containers and pipework for reactive and corrosive chemicals. Where used as a lubricant, PTFE reduces friction, wear, and energy consumption of machinery. It is commonly used as a graft material in surgical interventions. It is also frequently employed as a coating on catheters; this interferes with the ability of bacteria and other infectious agents to adhere to catheters and cause hospital-acquired infections.

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